Efforts for health system transformation (HST) are taking place in diverse sites across the healthcare industry, involving stakeholders at many levels. In this context, co-production as an approach to HST is gaining traction, but its impact remains unclear. We compared and contrasted the findings from evaluations of three initiatives that adopted co-productive methods to promote HST. The first initiative evaluated clinicians’ perspectives on HST using qualitative methods. The other two initiatives evaluated the perspectives of healthcare consumers-advocates using a mixed-method approach. Findings from these evaluations show that using co-productive methods can create a space where power dynamics can be renegotiated to promote process changes that may result in outcomes of more inclusive, consumer-centered health policies and improved health outcomes.